Dave joined 10TV Eyewitness News in July 1980. His most visible public service work was at on-the-scene assignments. He co-anchored 10TV’s Annual Food Parade...central Ohio’s contribution to Operation Feed, which is the largest local community food drive in the world. He also co-anchored the Children’s Miracle Network Telethon for more than 10 years.

Dave has covered a wide array of news stories in his career including coverage of the 1984 Democratic National Convention from San Francisco and the 1996 Republican National Convention from San Diego. He also covered the Republican National Convention from Philadelphia in 2000 and both Republican and Democratic National Conventions in 2004. He anchored live from Graceland mansion after the death of Elvis Presley. He produced a news series on Cuban refugees from Fort Chaffee, Arkansas. He also joined the manhunt for James Earl Ray (the assassin of Martin Luther King Jr.) during an escape attempt from a Tennessee penitentiary.

In 1977, Dave was responsible for the Tennessee coverage of President Jimmy Carter’s inauguration and spent four days with Miss Lillian Carter, the president's mother, to produce an exclusive series on the mother of the president from Plains, Georgia. Dave was the only reporter from a Columbus TV station to be on-the-scene in Berlin during the historic crumble of the Berlin Wall. After the tragedy in Oklahoma City, Dave Kaylor was there, broadcasting information live as it came in for four days. He completed a demanding undercover assignment that involved disguising himself to reveal the plight of panhandlers on Columbus’s city’s streets.

In 1998, Dave completely covered Senator John Glenn’s return to space, from Glenn’s announcement in Washington early in the year to his lift off in October. Dave filed reports from Washington, Houston, and Cape Canaveral. He also co-anchored the three-hour special report on the day of lift off and anchored Glenn’s return with former astronaut Kathryn Sullivan. 

Election 1998 was important for the state of Ohio as it elected a new governor and U.S. senator. Dave was the moderator of the gubernatorial debate, which was carried statewide and on C-Span nationwide. In 1999 Dave covered President Clinton’s Impeachment doing live reports from Washington D. C., and followed that in 2000 by covering the Republican National Convention. 

Within hours of the September 11 attack at the Pentagon, Dave and a crew drove to Washington D.C.,  filing reports on the tragedy that same day.

Dave’s dedication and commitment to news reporting earned him two Regional Emmy nominations for his role as host of “Capital Square,” a weekly one half-hour 10TV program about state political and legislative issues. In 1996 he was awarded the Best Male Anchor of the Year in Large Markets by the National Academy of Television Journalists in Washington, D. C. He received two Emmys for the weekly program “Capital  Agenda”. Dave has received numerous awards from community groups for his work with community affairs.

Dave retired on August 18, 2005 from WBNS-10TV after 25 years at the station and almost 40 years in the broadcast news profession. However, his interest in political reporting brought him back to WBNS-10TV during the fall of 2006 when he filed live reports from Ohio’s major cities on the Gubernatorial and U.S. Senate races as well as the statewide issues on the ballot. The program was called “On the Road with Dave Kaylor.” The title of the program relates to Dave’s work as a co-anchor and reporter on a 1987 series entitled “The Heart of Ohio,” when Dave, his co-anchor and crew went on the road for a six-week period leaving Columbus on Monday and returning on Fridays after visiting historic and notable sites all around Ohio. Each show ran for a half hour “Live” from each location. The program was to last just six weeks but ran for almost five years taking on different forms and production values as the industry evolved and the technology changed. Dave has always said that the days during “The Heart of Ohio” broadcasts were some of his favorites “because the content was informative, entertaining, and you felt you were making a difference, as was indicated by the many letters recieved in responce from the viewing audience."

Dave was inducted into The Ohio Associated Press Broadcasters Associations’ Hall of Fame on July 10, 2007.